A critical concern / Heart rhythm
Serious cardiac effects can occur.
Ibogaine can prolong the heart’s QT interval and trigger dangerous abnormal rhythms, including cardiac arrest. It can also slow the heart rate.
Risk may be increased by existing heart conditions, some medicines, and electrolyte imbalances. A person can have an underlying problem without knowing it.
A normal ECG alone does not establish that treatment is safe. Risk can persist beyond the main psychoactive experience.
Medicines and substances can interact.
Prescription medicines, non-prescription products, supplements, alcohol and other drugs may affect heart rhythm, drug metabolism or mental state. Do not stop or adjust medicines to prepare on your own.
Physical and mental health matter.
Seizures, impaired coordination, vomiting and aspiration are concerns. Liver disease and a history of severe mental illness may also affect risk and require specialist assessment.
Withdrawal needs its own care plan.
Alcohol and benzodiazepine withdrawal can be life-threatening. Dependence and withdrawal must be medically assessed; ibogaine is not a substitute for supervised withdrawal care.